According to researchers, most eczema cases are due to the lack of a protein called filaggrin. Understanding this key element has allowed them to further research why eczema causes a skin pile-ups instead of shedding, which interferes with skins natural ability to keep fluids in and evaders out. Which ultimately puts us eczema sufferers at risk of infections. Causing the wrong bacteria to grow and making it easy for allergens to cause immune responses – thus the itching and scratching cycle.
There’s a specific protein in bee venom called melittin, which has been shown to suppress the immune system. The researchers did this by testing and finding results on mice.
To dig into melittin’s potential as an anti-inflammatory, the team divided a number of mice into nine groups, and used three of them to test various doses of melittin and bee venom on mice sensitised to have an atopic dermatitis-like skin condition.
The other groups of mice served as controls, so the team could compare their results with a placebo, and also test it on mice which hadn’t been sensitised.
Similar tests were also carried out on human skin cell tissues, which were also dosed with increasing amounts of melittin.
In both models, bee venom – in particular, melittin – effectively reduced the inflammation responsible for much of the discomfort caused by this skin condition, indicating it could be a good candidate for a topical treatment.
An analysis of the biochemical and cellular changes in the human and mouse tissues suggests just how the protein might manage this by blocking the expression of chemical messengers called cytokines.
Whether this will actually help eczema patients, only time will tell, but this is a very unique source of nature doing what it does best…healing!